Limit vardenafil dose to 5 mg/24 hr erythromycin lactobionateerythromycin lactobionate will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Why is this medication prescribed?
grapefruitgrapefruit will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. grapefruit will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. griseofulvingriseofulvin will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. griseofulvin will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. haloperidolhaloperidol and vardenafil both increase QTc interval.
Uses of This Medicine:
haloperidol and vardenafil both increase QTc interval. hydrocortisonehydrocortisone will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. hydrocortisone will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. hydroxyzinehydroxyzine and vardenafil both increase QTc interval. hydroxyzine and vardenafil both increase QTc interval.
Corresponding author
ibrexafungerpibrexafungerp will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors imatinibimatinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors imatinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors Drugs that are known to prolong the QTc interval may have an increased the risk of ventricular arrhythmias. Drugs that are known to prolong the QTc interval may have an increased the risk of ventricular arrhythmias. Limit vardenafil dose to 5 mg/24 hr erythromycin stearateerythromycin stearate will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Limit vardenafil dose to 5 mg/24 hr erythromycin stearate will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Limit vardenafil dose to 5 mg/24 hr escitalopramescitalopram increases toxicity of vardenafil by QTc interval. escitalopram increases toxicity of vardenafil by QTc interval. eslicarbazepine acetate will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
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Transient decrease in heart rate and AV conduction delays may occur when initiating etrasimod. Owing to potential of additive effect on heart rate, etrasimod may increase risk of QT prolongation and Torsades de Pointes when coadministered with Class Ia or Class III antiarrhythmic drugs, or other drugs that prolong the QT interval.
| Advice | Explanation | Additional Notes |
|---|---|---|
| Take on an empty stomach or after light meal | Food, especially high-fat meals, can delay absorption | Best taken at least 30 minutes before sexual activity |
| Do not exceed prescribed dose | Risk of side effects or interactions | Follow healthcare provider guidance |
| Avoid alcohol consumption | Excessive alcohol can increase risk of side effects | Moderate intake may be acceptable |
| Report adverse effects promptly | Includes vision changes, prolonged erections, severe dizziness | Seek immediate medical help if needed |
etravirineetravirine will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. etravirine will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. fedratinibfedratinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
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fostamatinibfostamatinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fostamatinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fostemsavirvardenafil and fostemsavir both increase QTc interval. QTc prolongation reported with higher than recommended doses of fostemsavir. vardenafil and fostemsavir both increase QTc interval.
What should I know about vardenafil before taking it?
gemifloxacingemifloxacin and vardenafil both increase QTc interval. gemifloxacin and vardenafil both increase QTc interval. gepirone and vardenafil both increase QTc interval. gepotidacingepotidacin increases levels of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. If possible, avoid with sensitive substrates that are are extensively metabolized by CYP3A4 and have a narrow therapeutic index.
Dosage Modifications
If unable to avoid, monitor or modify substrate dose according to its prescribing information. gepotidacin increases levels of vardenafil by affecting hepatic/intestinal best ed treatments enzyme CYP3A4 metabolism. gilteritinib and vardenafil both increase QTc interval. granisetrongranisetron and vardenafil both increase QTc interval. granisetron and vardenafil both increase QTc interval. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fedratinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fexinidazolefexinidazole will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fexinidazole will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fingolimodfingolimod and vardenafil both increase QTc interval. fingolimod and vardenafil both increase QTc interval. fluconazolefluconazole will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
- Vardenafil is sometimes used off-label for other circulatory issues.
- It is important to avoid using if you have a history of stroke.
- Consult your healthcare provider if you experience chest pain.
- Patients with ocular conditions should use caution.
- Vardenafil may cause a drop in blood pressure.
- The medication should be stored away from heat and moisture.
- It is safer to take Vardenafil under medical supervision.
- Lifelong medical monitoring may be required in some cases.
- Vardenafil is not suitable for men with certain heart conditions.
- Combining with nitrates can cause dangerous hypotension.
- Always read the medication guide before use.
Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fluconazole will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fludrocortisonefludrocortisone will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. fludrocortisone will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. fluvoxaminefluvoxamine will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fluvoxamine will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosamprenavirfosamprenavir will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosamprenavir will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosaprepitantfosaprepitant will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosaprepitant will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Overdose/Missed Dose
Limit vardenafil dose to 5 mg/24 hr erythromycin lactobionateerythromycin lactobionate will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Limit vardenafil dose to 5 mg/24 hr erythromycin stearateerythromycin stearate will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Limit vardenafil dose to 5 mg/24 hr erythromycin stearate will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Limit vardenafil dose to 5 mg/24 hr escitalopramescitalopram increases toxicity of vardenafil by QTc interval. escitalopram increases toxicity of vardenafil by QTc interval.
5.2 Serious Adverse Effects and Precautions
eslicarbazepine acetate will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Transient decrease in heart rate and AV conduction delays may occur when initiating etrasimod. Owing to potential of additive effect on heart rate, etrasimod may increase risk of QT prolongation and Torsades de Pointes when coadministered with Class Ia or Class III antiarrhythmic drugs, or other drugs that prolong the QT interval. etravirineetravirine will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. etravirine will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
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fedratinibfedratinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fedratinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fexinidazolefexinidazole will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fexinidazole will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fingolimodfingolimod and vardenafil both increase QTc interval. Vardenafil dose may need to be lovegra women reduced if coadministered with moderate or strong CYP3A4 inhibitors fosfomycinfosfomycin and vardenafil both increase QTc interval.
Adverse reactions
The risk of QT prolongation may increase in patients with electrolyte abnormalities (such as hypokalemia and hypocalcemia), patients with conditions that have potential to cause electrolyte imbalance (such as renal impairment), or patients taking other drugs affecting electrolyte balance or QT prolongation; avoid this drug in patients with known QT prolongation or ventricular arrhythmias, including a history of torsade de pointes; monitor electrolytes during treatment fosfomycin and vardenafil both increase QTc interval. The risk of QT prolongation may increase in patients with electrolyte abnormalities (such as hypokalemia and hypocalcemia), patients with conditions that have potential to cause electrolyte imbalance (such as renal impairment), or patients taking other drugs affecting electrolyte balance or QT prolongation; avoid this drug in patients with known QT prolongation or ventricular arrhythmias, including a history of torsade de pointes; monitor electrolytes during treatment fosphenytoinfosphenytoin will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. fosphenytoin will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. fostamatinibfostamatinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fostamatinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Benefits of Levitra Jelly
Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors isavuconazonium sulfate will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors isoniazidisoniazid will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors isoniazid will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors istradefyllineistradefylline will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fostemsavirvardenafil and fostemsavir both increase QTc interval. QTc prolongation reported with higher than recommended doses of fostemsavir. vardenafil and fostemsavir both increase QTc interval.
- Vardenafil's active ingredient is vardenafil hydrochloride.
- It is often preferred for its rapid onset compared to others.
- It can be used successfully in men with nerve damage.
- Vardenafil may cause temporary visual color changes.
- It is not suitable for individuals with severe heart failure.
- Alcohol can impair the effectiveness of vardenafil.
- Taking it on an empty stomach may improve absorption.
- Avoid driving or operating machinery after taking Vardenafil.
- It is important to follow-up with your healthcare provider regularly.
- Do not double dose if the first dose is ineffective.
- Use the lowest effective dose to minimize side effects.
gemifloxacingemifloxacin and vardenafil both increase QTc interval. gemifloxacin and vardenafil both increase QTc interval. gepirone and vardenafil both increase QTc interval. gepotidacingepotidacin increases levels of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
- Vardenafil is a prescription medication for erectile dysfunction.
- It works by relaxing blood vessels in the penis.
- The drug's effectiveness depends on sexual arousal.
- Vardenafil is often taken before planned sexual activity.
- It is not a cure but a temporary solution for ED.
- Patients should inform their doctor of all current medications.
- Report any sudden vision loss or hearing issues promptly.
- Vardenafil's safety profile is well established when used correctly.
- The medication is part of a class of PDE5 inhibitors.
- It is not recommended to combine with recreational drugs.
- Some users report relief within 15-30 minutes of intake.
If possible, avoid with sensitive substrates that are are extensively metabolized by CYP3A4 and have a narrow therapeutic index. If unable to avoid, monitor or modify substrate dose according to its prescribing information. gepotidacin increases levels of vardenafil by affecting hepatic/intestinal best ed treatments enzyme CYP3A4 metabolism. gilteritinib and vardenafil both increase QTc interval. granisetrongranisetron and vardenafil both increase QTc interval. granisetron and vardenafil both increase QTc interval. grapefruitgrapefruit will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. grapefruit will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. griseofulvingriseofulvin will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. griseofulvin will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. haloperidolhaloperidol and vardenafil both increase QTc interval. haloperidol and vardenafil both increase QTc interval.
What other information should I know?
fingolimod and vardenafil both increase QTc interval. fluconazolefluconazole will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fluconazole will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fludrocortisonefludrocortisone will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. fludrocortisone will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
How should I store vardenafil?
fluvoxaminefluvoxamine will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fluvoxamine will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosamprenavirfosamprenavir will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosamprenavir will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosaprepitantfosaprepitant will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Treatment & Diagnosis
Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosaprepitant will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be lovegra women reduced if coadministered with moderate or strong CYP3A4 inhibitors fosfomycinfosfomycin and vardenafil both increase QTc interval. The risk of QT prolongation may increase in patients with electrolyte abnormalities (such as hypokalemia and hypocalcemia), patients with conditions that have potential to cause electrolyte imbalance (such as renal impairment), or patients taking other drugs affecting electrolyte balance or QT prolongation; avoid this drug in patients with known QT prolongation or ventricular arrhythmias, including a history of torsade de pointes; monitor electrolytes during treatment fosfomycin and vardenafil both increase QTc interval. The risk of QT prolongation may increase in patients with electrolyte abnormalities (such as hypokalemia and hypocalcemia), patients with conditions that have potential to cause electrolyte imbalance (such as renal impairment), or patients taking other drugs affecting electrolyte balance or QT prolongation; avoid this drug in patients with known QT prolongation or ventricular arrhythmias, including a history of torsade de pointes; monitor electrolytes during treatment fosphenytoinfosphenytoin will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. fosphenytoin will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. hydrocortisonehydrocortisone will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. hydrocortisone will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. hydroxyzinehydroxyzine and vardenafil both increase QTc interval. hydroxyzine and vardenafil both increase QTc interval. ibrexafungerpibrexafungerp will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors imatinibimatinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors imatinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors Drugs that are known to prolong the QTc interval may have an increased the risk of ventricular arrhythmias. Drugs that are known to prolong the QTc interval may have an increased the risk of ventricular arrhythmias. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors isavuconazonium sulfate will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
| Condition | Recommendation | Notes |
|---|---|---|
| Concurrent nitrate therapy | Do not use | Risk of severe hypotension |
| Severe cardiac conditions | Consult healthcare provider | Use with caution |
| Liver impairment | Dose adjustment needed | Due to metabolism via liver |
| Allergic reaction to vardenafil | Discontinue use | Immediate medical attention |
Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors isoniazidisoniazid will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
| Country | Legal Status | Purchase Regulations |
|---|---|---|
| United States | Prescription-only medication | Requires prescription from licensed physician |
| European Union | Prescription required | Available at licensed pharmacies |
| India | Over-the-counter in some regions | Varies by jurisdiction |
| Australia | Prescription-only medication | Prescription required |
Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors isoniazid will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors istradefyllineistradefylline will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.